Acne-associated bacterial growth is an important consideration in skin health. This study evaluated the in vitro inhibitory activity of an ethanol extract of mango ginger, Curcuma mangga Val. & Zijp, rhizomes against Staphylococcus aureus and Cutibacterium acnes (formerly Propionibacterium acnes). Antibacterial activity was assessed using the agar well-diffusion method. Medi-Klin® 1% gel and distilled water were used as the positive and negative controls, respectively. The data were analyzed using analysis of variance (ANOVA), with a significance level of 0.05. The analysis indicated a statistically significant difference among the tested treatments (reported by SPSS as p = 0.000; this should be reported as p < 0.001). The extract inhibited both bacterial species, although its reported inhibitory activity was approximately half that of the positive control. These findings indicate in vitro antibacterial activity; further testing is needed to characterize its magnitude and establish its potential application.
Keywords
Curcuma mangga, ethanol extract, antibacterial activity, agar well-diffusion, Staphylococcus aureus, Cutibacterium acnes